rises with muscle mass, so an adult range over-reads a child
Glucose
3.5–5.5 mmol/L (63–99 mg/dL)
newborn above 2.6 mmol/L
Urine sodium / chloride
under 20 mmol/L means the loss is not renal
a high urine chloride points to the kidney or a diuretic
Liver, bone and metabolic
Measure
Reference
Note
ALT / AST
10–40 / 10–45 U/L
GGT
5–35 U/L
up to 200 in the first months of life
Alkaline phosphatase
child 100–400 U/L, higher in the growth spurt
an adult range makes normal childhood bone turnover look like disease
Bilirubin (total)
under 17 µmol/L (1 mg/dL) beyond the newborn period
Conjugated bilirubin
under 17 µmol/L, or under 20 percent of total
above this is always pathological
Albumin
35–50 g/L
Ammonia
newborn under 110, child under 50 µmol/L
Calcium / magnesium / phosphate
2.2–2.7 / 0.7–1.0 / 1.2–2.0 mmol/L
phosphate runs higher in infancy, to about 2.6
Lipase or amylase
three times the upper limit defines pancreatitis
Sweat chloride
under 30 normal, 30–59 intermediate, 60 or more diagnostic
Cerebrospinal fluid
Measure
Newborn
Child
White cells
0–20 /mm3
0–5 /mm3
Protein
0.4–1.2 g/L
0.15–0.45 g/L
Glucose
at least 60 percent of the blood glucose
at least 60 percent of the blood glucose
Bacterial pattern
hundreds to thousands of neutrophils, high protein, low glucose
same
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Haematology – Exam Review Set 1 in 50 board-style clinical cases with worked explanations. Each case gives you a clinical vignette, four options, the correct answer, and an explanation of why each of the other three is wrong, with the guideline or textbook it follows named on the answer.
Board-style teaching questions for paediatricians and trainees preparing for paediatric board, MRCPCH and licensing examinations. Written from published guidelines and standard paediatric textbooks, with the source named on every answer.
The 50 cases, in order
Too much milk, and pencil shapes
Helmets and triangles
Dots near the edge
Iron in a ring, and none used
Every index heading down
Dense round cells, no pale middle
Born early, and running short
A stroke at nine
Like father, like son
His brother needed transfusions
Bruises two weeks after a cold
The nosebleed that would not stop
Bruised but well at fifty
Big platelets, blue inclusions
The receptor that is missing
Nose, gums, and now her periods
Where the defect lies
A knee swollen after a small fall
The dose that did not work
An inhibitor with a low titre
Twenty kilograms, fifty per cent
The formula for the dose
The third time in a year
The tablet taken at home
Long in the tube, clots in the leg
Everything abnormal at once
Born at home, bruised on day five
Six weeks, and a bulging fontanelle
Pale but not yellow
Red, jittery and thick
Three pneumonias on penicillin
The second day of the crisis
Pale, and the belly suddenly full
Reticulocytes at zero
Six months, pale, a spleen
Yellow a week after a cold
Dark urine three days later
The yearly scan of the arteries
The regulator in the acid
Inflamed, anaemic, and which one
A sibling who matches
The thumb that was missing
When the aplasia is severe
Five of the same letter
What one bag should achieve
The new fridge
Spiky cells and fatty stools
Who needs iron early
One hundred per cent of one kind
Rods inside the blasts
Diagnoses and management options tested
Across the fifty cases you are asked to choose between options such as: Target cells, Hypochromic microcytic anaemia, Continue breast milk and give an iron supplement, A bone marrow aspirate under general anaesthetic, Platelet transfusion, Haemophilia A, Platelets, The desired increase times weight times 0.5, Vitamin K deficiency, Birth trauma from a difficult delivery, No T cells, Splenic sequestration of blood, Paracetamol, Haemoglobin electrophoresis.
Clinical pearls from this deck
The distribution width separates iron deficiency from thalassaemia trait.
Fragments plus low platelets plus kidneys: think of the small vessels.
The spleen you could feel at two is gone by six, and so is its filter.
Try pyridoxine first; many respond.
Ferritin first, haemoglobin last.
A high MCHC is rare, and spherocytosis is the usual reason.
Work through the deck once for recognition, then again a week later to test yourself — each question gives the answer and explains why every other option fails.