G6PD Deficiency – Board-Style Questions

What this deck covers

G6PD Deficiency in 18 board-style clinical cases with worked explanations. Each case gives you a clinical vignette, four options, the correct answer, and an explanation of why each of the other three is wrong, with the guideline or textbook it follows named on the answer.

Board-style teaching questions for paediatricians and trainees preparing for paediatric board, MRCPCH and licensing examinations. Written from published guidelines and standard paediatric textbooks, with the source named on every answer.

The 18 cases, in order

1. Cousins planning a family
2. Not only boys
3. A map of an old infection
4. Which chart line
5. A family celebration
6. Where it is common
7. A result that is not his
8. From the wardrobe
9. Nothing he ate
10. Nothing given to him
11. Eaten many times before
12. Before the first cycle
13. Grey-blue on dapsone
14. Four sensitive drugs
15. A normal screen in a girl
16. Normal level, open question
17. Settling on its own
18. Still dark on every sample

Diagnoses and management options tested

Across the 18 cases you are asked to choose between options such as: No daughter affected, as each gets one normal X, She must have a second, unrelated red cell defect, It gives some protection against falciparum malaria, Against the exchange line, because he is a boy, Breast milk jaundice arising in the first week, Test every newborn, girls as well as boys, Now, at three weeks, on a fresh sample, Autoimmune haemolysis after a recent viral illness, The viral infection, through oxidant stress, Across the placenta, weeks before birth, Only raw beans are a risk, so cooked ones are safe, Rasburicase at half dose, with close monitoring, Exchange transfusion, not methylene blue, Nitrofurantoin, the usual first-line choice.

Clinical pearls from this deck

• Two carriers of an X-linked gene can have homozygous daughters.
• A heterozygous girl is not always a silent carrier: lyonisation decides.
• Where malaria was, G6PD deficiency is.
• A G6PD-deficient newborn is plotted against the risk-factor line.
• In a G6PD-deficient newborn, henna is an oxidant, not a decoration.
• Common locally means screen universally.

Work through the deck once for recognition, then again a week later to test yourself — each question gives the answer and explains why every other option fails.

More from this system: all Haematology case decks · pediatric reference values.