Autoimmune Hepatitis – Board-Style Questions

What this deck covers

autoimmune hepatitis in 18 board-style clinical cases with worked explanations. Each case gives you a clinical vignette, four options, the correct answer, and an explanation of why each of the other three is wrong, with the guideline or textbook it follows named on the answer.

Board-style teaching questions for paediatricians and trainees preparing for paediatric board, MRCPCH and licensing examinations. Written from published guidelines and standard paediatric textbooks, with the source named on every answer.

The 18 cases, in order

1. A young girl, acutely
2. Tired for months
3. What the biopsy shows
4. No antibodies found
5. Thrush and tetany
6. Looking at the ducts
7. Worried about her face
8. Is she better yet
9. Two years of acne
10. Rising again at 15
11. Cannot take the tablets
12. Nothing has worked
13. Can I stop now
14. Failing without coma
15. The ducts are narrow
16. Starting treatment
17. A short history
18. Years after the graft

Diagnoses and management options tested

Across the 18 cases you are asked to choose between options such as: Anti-mitochondrial M2 antibody, Antinuclear and anti-smooth muscle antibodies, Florid duct lesions with portal granulomas, Withhold treatment until antibodies appear, AIRE, the thymic immune regulator, It is needed to measure the liver fibrosis, Methotrexate by weekly injection, Negative autoantibody titres now, Oral minocycline, Disease resistant to azathioprine, Oral cyclophosphamide daily, A much higher dose of azathioprine alone, Stop only if a biopsy shows no activity, Azathioprine alone until the INR has fallen.

Clinical pearls from this deck

• Young child, acute onset: think anti-LKM-1.
• Older child, slow onset: ANA and smooth muscle antibodies.
• Plasma cells at the interface: the classic biopsy.
• No antibodies but typical biopsy: still treat.
• Candida plus low calcium plus hepatitis: look at AIRE.
• Scan the ducts at diagnosis: the duct form hides.

Work through the deck once for recognition, then again a week later to test yourself — each question gives the answer and explains why every other option fails.

More from this system: all Gastroenterology Board Questions case decks · pediatric reference values.