Congenital Hypothyroidism

What this deck covers

Congenital Hypothyroidism in thirteen clinical teaching cases with worked explanations. Each case gives you a clinical vignette, four options, the correct answer, and an explanation of why each of the other three is wrong.

Diagnoses and management options tested

Across the thirteen cases you are asked to choose between options such as: Goitre, bradycardia, pericardial effusion and anaemia, Palpable goitre, Absent thyroid gland, Discontinue the medication for 30 days, Ectopic thyroid gland, Thyroid agenesis, Maternal TSH receptor blocking antibodies (TSBAb), DUOX2 mutation, Congenital hepatic haemangioma.

Clinical pearls from this deck

• Maternal T4 crosses the placenta and partially protects the fetus, masking symptoms for roughly 2 weeks after birth. That is why only 1–4% of infants with CH are diagnosed clinically at birth — almost all look entirely well.
• The early signs at 2–6 weeks are subtle and easily attributed to normal newborn variation — prolonged jaundice is the commonest, alongside constipation, feeding difficulty, hypotonia, large anterior and posterior fontanelles, hypothermia, lethargy and a hoarse cry.

The thirteen worked cases in this deck, with the images and the full explanation of every option, are part of Pediatric Case Review membership. See what is included.

More from this system: all metabolic and genetic decks and question sets · pediatric reference values.