Ewing Sarcoma and Osteosarcoma – Board-Style Questions

What this deck covers

Ewing sarcoma and osteosarcoma in 18 board-style clinical cases with worked explanations. Each case gives you a clinical vignette, four options, the correct answer, and an explanation of why each of the other three is wrong, with the guideline or textbook it follows named on the answer.

Board-style teaching questions for paediatricians and trainees preparing for paediatric board, MRCPCH and licensing examinations. Written from published guidelines and standard paediatric textbooks, with the source named on every answer.

The 18 cases, in order

1. The rim around the shaft
2. Rays from the surface
3. Where each one settles
4. Unwell as well as sore
5. What the laboratory looks for
6. A panel run before the result
7. The pink material
8. Something in the early years
9. Looking further than the limb
10. Where the needle goes in
11. Before the operation
12. The drugs used first
13. When beams are useful
14. Which spread is worst
15. A leg that must keep pace
16. A check that never stops
17. Asking again at the back
18. A conversation before day one

Diagnoses and management options tested

Across the 18 cases you are asked to choose between options such as: A dense sclerotic band sealing the lesion from the marrow, Bone streaks radiating at right angles with a raised cuff, The growing end of the femur and the upper end of the tibia, A muscular strain that has been repeatedly aggravated, A fusion of EWSR1 with FLI1 from a translocation of 11 and 22, Nuclear staining for myogenin throughout the section, Lobules of cartilage with cells inside lacunae, The absence of any injury to the knee before the pain, The lungs, well before any other organ is involved, It determines how much local anaesthetic the child will need, It allows the growth plates to close before any operation, Rituximab with bendamustine and a short steroid course, The first can be irradiated; the second must be removed, A single small deposit within one lung.

Clinical pearls from this deck

• Parallel sheets along a shaft: the onion skin.
• Rays at right angles with a raised cuff: osteosarcoma.
• Ewing takes the shaft and the flat bones.
• Fever and weight loss can belong to the tumour itself.
• Ewing sarcoma is defined by its EWSR1 fusion.
• CD99 at the membrane supports Ewing sarcoma.

Work through the deck once for recognition, then again a week later to test yourself — each question gives the answer and explains why every other option fails.

More from this system: all MSK and orthopaedics case decks · pediatric reference values.