Juvenile Myasthenia Gravis – Board-Style Questions

Juvenile Myasthenia Gravis — Board-Style Questions
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Pediatric Case ReviewBoard-Style Questions
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What this deck covers

juvenile myasthenia gravis in 18 board-style clinical cases with worked explanations. Each case gives you a clinical vignette, four options, the correct answer, and an explanation of why each of the other three is wrong, with the guideline or textbook it follows named on the answer.

Board-style teaching questions for paediatricians and trainees preparing for paediatric board, MRCPCH and licensing examinations. Written from published guidelines and standard paediatric textbooks, with the source named on every answer.

The 18 cases, in order

  1. Worse by teatime
  2. How the antibody harms
  3. Cold on the lid
  4. No antibodies found
  5. Looking behind the sternum
  6. Since the first months
  7. Two tests negative
  8. Only the eyes so far
  9. The eye behind the lid
  10. The first tablet
  11. Cramps after each dose
  12. Extra doses at home
  13. Worse on the ward
  14. Weaker in the first week
  15. Before the steroid-sparing drug
  16. An operation to consider
  17. Planning the anaesthetic
  18. Neck and throat first

Diagnoses and management options tested

Across the 18 cases you are asked to choose between options such as: A third nerve palsy, Complement attack on the postsynaptic membrane, A drop of phenylephrine in the eye, Absent sensory nerve action potentials in the legs, Imaging of the mediastinum for thymoma, Seronegative autoimmune myasthenia, Voltage-gated calcium channel, Almost all children generalise within a year, Amblyopia from the lid blocking vision, Intravenous edrophonium, Viral gastroenteritis by chance, A myasthenic crisis from the illness, Gentamicin, Steroid-induced myopathy.

Clinical pearls from this deck

  • Fatigable ptosis with normal pupils: myasthenia.
  • Myasthenia: complement damages the postsynaptic membrane.
  • Varying ptosis: try an ice pack over the lid.
  • Seronegative myasthenia: look for decrement and jitter.
  • Confirmed myasthenia: image the mediastinum.
  • Infant onset, no antibodies: congenital myasthenia.

Work through the deck once for recognition, then again a week later to test yourself — each question gives the answer and explains why every other option fails.

More from this system: all Neurology case decks · pediatric reference values.

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